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ADRENAL FATIGUE PROTOCOL

Woman lying with her head next to a cup of coffee on her office desk

ADRENAL FATIGUE PROTOCOL : Here are a number of things that you can do to assist with managing the condition:

 

  1. Removal of the stressors: This is the most important step.  Emotional stressors such as marital, family, relationship or financial problems need to be dealt with and normalized.
  1. Sleep: It is important is to have enough rest.  Try to go to sleep by 10 pm every night.

This is required because our adrenal glands kick in for a “second wind” from 11 pm to 1 am.  This puts enormous stress on the adrenals.  When we rest early our adrenals are fully rested and the high gear is avoided.  Between 10 pm and 1 am our adrenals work hardest to repair the body.  We should also try to sleep in until 8.30 am or 9 am if possible.  This is because our cortisol level rises to its peak from 6 am to 8 am in order to wake up and get us going for the day.

In the later stage of adrenal fatigue, the level of cortisol fails and we feel tired.  It becomes more difficult to wake up.  If we wake up to early, this will only increase stress on the adrenal glands, which will have to produce more cortisol while they are already exhausted.

A good night’s sleep is therefore mandatory.  Without a good sleep, our bodies cannot regenerate to deal with stressors the next day.  We should also rest in a complete dark room to maximize melatonin production.

If you are unable to fall asleep, you may want to try a herbal product called SEDAZONE. Normally taken at a dosage of 2 – 3 capsules after supper.

Another good natural sleep enhancer is called MEMORY PLUS. This product contains Bluenesse (an extract from Lemon Balm).  Dosage is normally 1 capsule after supper.

A tendency to wake up at 2 – 3 am and being unable to go back to sleep, is a sign of excessive stress.

  1. Avoid coffee and caffeinated beverages: Coffee and tea act as stimulants and interrupt the sleep pattern.  Herbal or Rooibos tea is acceptable because it does not contain caffeine.
  1. Avoid TV and computers: Some people may be photosensitive.  Watching TV or working at the computer in the late evening may prevent melatonin levels to rise to induce sleep.  If you are one of these people, you should turn off your television or computer by around 8 pm.
  1. Exercise: This is a wonderful stress reducer and a tremendous oxygenator.  Exercise reduces depression, increases blood flow, normalizes level of cortisol, insulin, blood glucose, growth hormone, thyroid and makes you feel generally much better.  You can exercise 20 to 30 minutes per day, at about 10 minutes per session.

 Simple exercise such as brisk walking, or climbing stairs are easy to do and can be done almost anywhere.  You should vary your routine so that exercise becomes fun.  Plan to burn about 2000 – 3000 calories each week.  When exercising you should try to cover the following three categories:

  • Aerobics – fast walking, stairs climbing, swimming, treadmill.
  • Anaerobics – weight lifting, push up, sit up, shin ups.
  • Flexibility –stretching, yoga, tai chi.
  1. Nutritional supplementation: It is prudent to optimize the adrenal gland functions.
  • Supplement with Adrenozone formula.  Three capsules daily, after breakfast.
  • 1000 mg – 2000 mg of Calcium ascorbate and ascorbyl palmitate (Double Vitamin C)
  • Vitamin E (mixed tocotrientols and tocopherols) is another important nutrient which is involved in at least 6 different enzymatic reactions in the adrenal cascade.
  1. Eating pattern: While our cortisol levels are at peak from 6 am – 8 am, we may have no appetite.  Many people skip breakfast because “they are not hungry”.  This is because our bodies need sugar to run.  Furthermore, our body’s energy requirement does not change during this period.  Even a small snack is better than nothing at all and will provide the needed energy even if there is no urge to eat.

Skipping breakfast is not a good idea.  If you are low on sugar, the adrenals are instructed to secrete cortisol because cortisol activates gluconeogenesis to increase blood sugar level and allow the body to function.  It is therefore important to have a healthy breakfast soon after waking and not later than 10 am.  This will prevent the body being put in a position of having to play “catch up” for the rest of the day.

The best time for lunch is from 11 – 11.30 am.  Sometimes, a nutritious snack between 2 – 3 pm will be needed to sustain our bodies through the dip in cortisol levels that occur between 3 – 4 pm.  Evening meals should be around 5 – 6 pm.  Supper should be in small quantities and low in glycemic index to avoid the steep rise in blood sugar commonly seen in high glycemic index snacks such as cakes.  These high GI snacks will cause the blood sugar to rise and a corresponding increase in insulin output.

Nightmares, anxiety, and night sweats.

Over time, insulin secretion becomes dysfunctional, resulting in a hypoglycemic state in the middle of the night.  These symptoms are characterized by nightmares, anxiety, and night sweats.  When this occurs, the body will have to activate the adrenals to put out more cortisol in order to raise the blood sugar back to its normal level.  This will eventually put an excessive burden onto the already fatigued adrenal glands if carried on year after year.

  1. Diet: A poor or unfitting diet is one of the key and leading causes of adrenal fatigue.  Without a diet that is bio-chemically and metabolically compatible with the needs of a damaged adrenal gland, complete recovery is simply not possible.

Sugar: 

Glucose is a simple sugar found in food.  It is an essential nutrient that provides energy for the proper functioning of the body cells.  After meals, food is digested in the stomach and is broken down into glucose and other nutrients.  The glucose is absorbed by the intestinal cells and carried by the bloodstream to cells throughout the body.  However, glucose cannot enter the cells by itself.  It needs assistance from insulin in order to penetrate the cell walls.  Insulin therefore acts as a regulator of glucose transport and metabolism in the body.

Insulin is called the “hunger hormone”.  As the blood sugar increases after a meal, the corresponding insulin level rises with the eventual lowering of the blood sugar level and glucose is transported from the blood into the cell for energy.  As energy is produced by the cell, and blood glucose level slowly is lowered; the insulin release from the pancreas is turned off.  As energy continues to be generated, the blood sugar level continues to drop.  When it drops below a certain level, hunger is felt.  This often occurs a few hours after the meal.  This drop in blood sugar triggers the adrenals to make more cortisol.  The cortisol increases the blood sugar by converting protein and fat into its component parts.  With this, the blood sugar rises to provide a continuous supply of energy for our use between meals.  Cortisol therefore works hand in hand with insulin to provide a steady blood sugar level 24 hours a day and keep blood glucose levels in a tightly controlled  range.

When the adrenal glands are in a fatigued state, the amount of cortisol production drops below the normal level, and the amount of sugar available to the cells is reduced.  With less sugar, less energy is available to the body and fatigue is experienced.  As the sugar level drops below a critical point, dizziness and light headedness can be experienced.  These are common symptoms of low blood sugar (hypoglycemia).  Low blood sugar is most likely experienced between 10 am – 12 pm as well as 3 – 4 pm.

To make things worse, the body’s automatic response when more sugar is needed during a stress response is to make more insulin in an attempt to move the sugar into the cell from the blood stream to create more energy.  Insulin opens up the cell membrane to push the glucose in, resulting in further reduction in blood glucose levels.  This worsens the already existing hypoglycaemic state.

Those with adrenal fatigue often report symptoms such as dizziness and weakness, as the blood sugar level drops below a comfortable level for the body to function normally.  To overcome this, the quick fix solution is to take food that is high in refined sugar such as a donut or sweets, or drinks which are stimulatory, such as coffee or cola drinks, to get the adrenals to put out more cortisol.  This gives the body a boost of energy.  However, this hypoglycaemic symptom relief lasts for only about 1 -2 hours.  Inevitably, it is followed by a crash to an even lower blood glucose level.  Those suffering from adrenal fatigue are constantly on a roller coaster ride in terms of their blood sugar level throughout the day.  The sugar level tends to increase after each quick fix, but drops after a few hours. By the end of the day, the body is totally exhausted.

A diet that maintains a constant sugar level in the blood is a critical consideration in adrenal fatigue recovery.  This can be done by taking a variety of low glycaemic index foods that releases sugar slowly to sustain the body during and between meals.  Starchy carbohydrates that are converted quickly into glucose (such as pasta and bread) should be limited.  Soda type drinks should be avoided totally.

Salt:

The amount of salt in the body is highly dependant and regulated by a chemical called aldosterone.  This chemical is manufactured in the adrenal cortex under the direction of another hormone called ACTH (adrenocorticotrophic hormone).  ACTH is produced by the anterior pituitary gland.

ATCH stimulates the adrenal cortex to secrete a wide variety of hormones including aldosterone as well as cortisol.  Like cortisol, aldosterone follows a diurnal pattern of secretion, peaking at 8 am and is at its lowest between 12 pm – 4 am.  Aldosterone is a very specific compound that is responsible for maintaining the concentration of sodium and potassium in the cells as well as outside the cell.  This in turn has a direct effect on the amount of fluid in the body.  Aldosterone therefore plays a significant part in regulating blood pressure.

It is important to note that in our body, sodium and water goes hand in hand.  Where sodium goes, water follows.  As the concentration of aldosterone rises in the body, the concentration of sodium and water rises, more fluid is retained in the body, and blood pressure rises.  Conversely, when the level of aldosterone lowers, the amount of sodium and water in the body is reduced.  The blood pressure goes down.

Unlike cortisol, aldosterone does not have its own negative feedback loop when there are excessive amounts.  If the aldosterone level is too high, aldosterone receptor sites will be down regulated and its sensitivity to aldosterone is reduced.  In the early phases of adrenal fatigue, the amount of cortisol and aldosterone increases in our body due to the ACTH stimulatory effect from stress.  As a result, the sodium and water is retained in the body with a feeling of bloatedness.

The baro-receptors (receptors that are sensitive to pressure) of the blood vessels are triggered and the blood vessels go into a relaxation mode automatically and this is regulated by the autonomic nervous system.  This auto regulation helps to maintain a stable blood pressure at a time when the total fluid volume increases due to a high level of aldosterone triggered by stress.   With stress, the adrenal glands also secrete another hormone called epinephrine.  This hormone constricts the blood vessels and increases blood pressure in order to ensure that our brain have adequate blood flow and oxygen to help us deal with impending danger.  The sum reaction of aldosterone, epinephrine and the autonomic relaxation response are some of the key factors that ultimately decide the final blood pressure at any point in time.  During the early stages of adrenal fatigue, the resulting blood pressure is often normal as if all bodily functions are well balanced.  If the body is unable to overcome the aldosterone and epinephrine response, the blood pressure is elevated.  It is common to find may people under stress, experiencing an increase in blood pressure.

As adrenal fatigue progresses to more advance stages, the amount of aldosterone production decreases.  Sodium and water retention is compromised.  As the fluid volume is reduced, low blood pressure ensues.  Cells get dehydrated and become sodium deficient.

People with advanced adrenal fatigue normally report low blood pressure as well as salt cravings.  The low blood pressure is due to the reduced fluid in the body.  Salt craving is because the body is in an absolute deficiency of sodium.  Both are due to the lack of aldosterone.  In order to compensate for this, potassium is leaked out of the cells so that the sodium to potassium ratio remains constant.  The loss of potassium is less than that of sodium, and as a result the potassium to sodium ratio is increased.  This imbalance creates another set of problems.

Those suffering from adrenal fatigue often have a low body fluid volume, accompanied by a salt craving due to absolute deficiency in sodium as well as a normal to high potassium level.  While lost fluid should be replaced, it has to be done carefully.  When the fluid is replaced without adequate sodium, the amount of sodium in the body actually gets diluted, therefore resulting in an even lower sodium level.  This is called dilutional hyponatremia, a dangerous condition that can be deadly.  It is therefore important to add salt liberally to fluids that are taken in by anybody suffering from adrenal fatigue.

Commonly available electrolyte replacement drinks such as Powerade or Energade are designed for people who have normal adrenal and excessive loss of potassium during exercise.  These drinks are designed to be high in potassium and low in sodium.  They can be taken in as fluid replacement if adrenal fatigue is very limited.  Sufferers of advanced adrenal fatigue usually have a low cortisol and sodium level.  They should rather take filtered water with ½ – 1 teaspoon of salt on a regular basis, especially in the morning.

Only a small number of people with adrenal fatigue have concurrent high blood pressure.  Those that fall into this category should check their blood pressure carefully during fluid replacement.

Hydration of a person in adrenal fatigue should take 24 – 48 hours.  The drink should be administered 2 – 4 times a day in intermittent dosages.  Coffee, alcohol and tea (with the exception of herbal tea) should be avoided.

Carbohydrate, Protein and Fats:

It is important for adrenal fatigue patients to balance the amount of protein, fat and carbohydrates.  As compared to a normal person, the adrenal fatigued person has an immediate need for sugar when hunger strikes.  At the same time, they also need good protein as well as good fat to have sustained energy until the next meal comes.

The primary diet should be high in raw food with a low glycaemic index.  Fruit juices should be avoided.  Whole fruit should be limited, especially melons, which are high in sugar and cause sugar spikes soon after the food enters the body.  Good quality protein from meat, fish and eggs are recommended.  These provide a steady source of energy to sustain the body between meals.

Vegetarians who have adrenal fatigue have a much bigger challenge.  Legumes (beans) must be eaten with whole grains, seeds or nuts to make a complete protein.  It is important for vegetarians to add eggs, miso, as well as combining beans, seeds, and nuts with a small amount of whole grain.  About 50 – 60 % of the diet should consist of raw food, and 6 – 8 servings of a wide variety of vegetables should be included.

Seeds and nuts are critical elements and sources of fatty acids, required by the adrenal glands to manufacture cholesterol, a precursor to adrenal steroid hormones.  The key is to take nuts and seeds that are raw and free of rancid oils.  Oils that are rancid make the symptoms of adrenal fatigue worse and should be avoided at all costs.  Raw nuts should be taken on a liberal basis and should be soaked overnight in water.  Nuts such as cashew, almond, brazil, pecan and chestnut are excellent.  Peanuts should be avoided.  Olive oil should be used cold on salads or for light cooking.  The cooking heat should be low to moderate.  Use coconut oil or butter for high heat or deep frying.

Vegetables high in sodium include kelp, black olives, red hot peppers, zucchini, spinach and Swiss chard.  Fruits should only be taken in moderation.  If you feel worse after food consumption, this is the body’s way of telling you that you are on the wrong track.  Organic fruit such as papaya, mango, apples, grapes and cherry are recommended.  Bananas, dates, figs, raisins and grapefruit are high in potassium and should be limited.

Many people with adrenal fatigue also have a lowered level of hydrochloric acid (HCI), which is necessary to break down protein.  Symptoms of this problem include gas, bloating and heaviness in the stomach after eating a meal containing protein.  In such case the use of Digestive enzymes and probiotics as well as Betaine Hydrochloride is recommended.

  1. Dietary Tips
  • Always eat breakfast and do it before 10 am. The body’s glycogen supply needs to be replenished after going through the night.  Try to eat your lunch before noon, followed by a nutritional snack between 2 – 3 pm.  The evening meal should be taken before 6 pm.  Just before bed time a couple of bites of high quality snacks are recommended.
  • Combine small amounts of whole grains with generous portions of protein and fat at every meal and snack except at bed time.  This will ensure sustained energy is available between meals.
  • Eat 20 – 25% whole grain, 30 – 40 % above the ground vegetables (50% of which should be raw), 10 – 15% beans, nuts and seeds, 10 – 20% animal food, 10 – 15% good fat, and 5 – 10% whole fruits    (except banana and fruits in the melon family).
  • Whole fruits are permitted for lunch and dinner – except banana, figs and those in the melon family.
  • Sprinkle sea salt liberally on food for a pleasant taste,  provided that blood pressure is normal.
  • Food that is high in potassium such as banana and dried figs can make the adrenals worse and should be avoided.
  • Start each morning with a full glass of water and ½ – 1 teaspoon of sea salt. The typical breakfast of fruits and yogurt will only worsen the adrenal fatigue sufferer.  In fact, those with adrenal fatigue usually experience and increase in shakiness after a breakfast high in fruit.  A good breakfast would be one that is high in protein and fats, such as eggs and raw nuts.  A small amount of grains is acceptable.
  • Eat 5 – 6 frequent small meals instead of 3 large meals.
  • Take a small amount of healthy snacks high in protein and fats such as cottage cheese or nuts before sleep if there is a tendency to wake up in the middle of the night.
  • Take a small amount of carbohydrate such as whole grain bread before sleep if there is difficulty to fall asleep.
 

SAMPLE DIETARY PLAN OF 2000 CALORIES A DAY:

20% Whole grain     = 400 calories = 2 slices of whole wheat bread, 1 cup of brown rice, ½ cup of oat meal.
30% Vegetables       = 600 calories = 3 cups salad, 2 cups green leafy vegetables, 2 cups mixed vegetables.
15% Nuts & seeds   = 300 calories = ½ cup legumes, 3 tablespoon of nuts and seeds.
15% Fat                     = 2 tablespoon olive oil.
10% Animal food     = 200 calories =2,5 oz of meat (including chicken or fish)
10% Whole fruits     = 200 calories= 2,5 medium fruit such as apple.

ADRENAL FATIGUE DIET

GOALS:

  1. Eat before 10 am . 
  2. Eat frequent, small meals: breakfast 6 – 8 am, Lunch 12 noon, Dinner at 6 pm, Snacks at 10 am, 3 pm and bed time.
  3. Eat 30 – 40% whole grains, 30 – 40% vegetables (50% should be raw), 10 – 15%  beans, seeds and nuts, 10 – 2-% animal foods, 5 – 10% fruit.

AVOID:

  • Banana, dried figs, raisins, dates, oranges, grapefruit  : High in potassium, makes situation worse
  • Fruit and juices in the morning : High in potassium and fructose
  • Refined flower products: pasta, white rice, bread : Drop blood sugar fast, robbed of nutrients
  • Pastry, baked good: cakes, biscuits
  • Coffee, tea, black tea, hot chocolate, colas, chocolates : Drop blood sugar too fast in 1 hour
  • Honey, sugar, syrup, soft drinks : Drop blood sugar too fast in 1 hour         
  • Dried fruit, fruit juices : Detrimental food early in morning, drop blood sugar too fast

 

PROTEIN:

 

GOOD CHOICE          REASONS           

  • Legumes               Soluble fiber        
  • Nuts                       High in monounsaturated fats     
  • Deep water fish    High in Omega 3 fatty acids  
  • Organic eggs        Best biological value protein for human   
  • Nuts                       Monounsaturated fats, (lowers cholest) fibers   

 BAD CHOICE          REASONS

  • Peanuts                 Aflatoxi (carcinogen)
  • Coastal fish          Toxic metals
  • Red meats            Acid forming, carcinogenic, hormones increase
  • Dairy                      Allergen, hormone increase

                 

 

FAT:

GOOD CHOICE               REASONS        

  • Avocado                    Monounsaturated fatty acid  
  • Olive oil                      Monounsaturated fatty acid  
  • Polyunsaturated       High in Omega 6 fatty acid

BAD CHOICE          REASONS

  • Margarine                Hydrogenated oil carcinogenic
  • Deep fried food       Hydrogenated oil carcinogenic   
  • Chips                        Hydrogenated oil when heated carcinogenic  
  • Saturated fats         Increase cholesterol    
  • Soft drinks               Acidic, high sugar                                                    
  • Desserts                  High sugar, high in Hydrogenated fat
  •  Sugar                    Empty calories, blood sugar spike                                                                                                       

 

 

TIPS FOR HEALTHY ADRENAL GLANDS:

#   Sleep by 10 p.m.
#   Sleep in until 9 a.m. if possible
#   Do the things you like
#   Avoid coffee or other caffeine containing beverages
#   Eat early
#   Have a glass of water in the morning with ½ – 1 teaspoon of sea salt
#   Avoid grains such as bread
#   Avoid starchy foods such as potato
#   Avoid trans-fats such as French fries
#   Take Adrenozone Formula, Vitamin C, Vitamin E, Magnesium
#   Avoid getting over tired
#   Avoid sugary fruit such as melons
#   Never skip breakfast               

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ADRENAL FATIGUE

woman in bed holding her head is suffering from adrenal fatigue

WHAT IS ADRENAL FATIGUE (also known as adrenal insufficiency, adrenal burnout or hypoadrenia)

Adrenal fatigue occurs when the adrenal glands, situated above the kidneys, become overworked and damaged, usually due to long term exposure to stress.  As a result of being overworked, they secrete reduced amounts of the adrenal hormones. The main ones being cortisol, aldosterone, pregnenolone, DHEA and adrenaline.  The most important of these is cortisol, since when this is lowered, the body will no longer be able to deal with stress, a situation which can lead to chronic fatigue syndrome.

 

WHAT ARE THE SYMPTOMS OF ADRENAL FATIGUE?   

The main symptom of adrenal fatigue is tiredness and chronic (long term) fatigue (especially in the morning and between 3 – 5 pm).  Other associated non-specific symptoms that could occur as a syndrome include chronic pain (especially upper back or neck), mild depression, anxiety, reduced stress coping ability (e.g. trembling under pressure, unexplained hair loss, insomnia, inability to loose weight (even though seriously trying to), poor blood sugar control (up or down), frequent infections, reduced sex drive, feeling better )up in the morning, worsening of allergies, reduced memory / concentration, alternating diarrhea and constipation and indigestion.

 

WHAT CAUSES ADRENAL FATIGUE?

The onset of adrenal fatigue is slow and insidious.  Chronic stress is the main cause of adrenal fatigue, since stress causes the adrenals to produce huge amounts of adrenal stress hormones.  This continues until the adrenals burn out and so does the supply of vital stress and anti-fatigue hormones.  As a result, chronic fatigue and the above mentioned symptoms of continued stress exposure begin.  Most adults experience adrenal fatigue of varying severities at some time in their lives.  Other causes of adrenal fatigue is constant anger (short fuse), chronic inflammation, chronic infections (such as Giardia and H. pylori which give rise to inflammation), chronic pain, excessive exercise, low blood sugar, surgery foods, excessive sugar, caffeine or alcohol intake and toxin exposure (such as smoking or environmental pollutants).

 

ADRENAL FATIGUE VERSUS ADRENAL NON FUNCTION

Adrenal fatigue (very common) should not be confused with another medical condition called Addison’s disease where the adrenal glands are not functioning (very rare).  While Addison’s disease is often caused by auto-immune dysfunction, adrenal fatigue is caused by stress.

 

A SUGGESTED NATURAL REMEDY FOR ADRENAL FATIGUE:

Adrenozone is a natural complex formulated to restore adrenal function. Read more on Adrenozone

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BOTTLED WATER – THE LETHAL HABIT

A hand holding a glass of water next to a hand holding a bottle of water

“I feel so out of it” she said, clutching her little bottle of water.

No wonder she felt “out of it”, because her little body was most probably being overwhelmed by some gender bending chemicals, courtesy of her little plastic water bottle.

 

Mankind’s love affair with plastic bottles

 

Mankind’s love affair with plastic bottles filled with water, represents the pinnacle of human irrationality.  Despite rising awareness of the global environmental plastics disaster we have created, the trend of consuming vast amounts of an expensive product we do not need (what is wrong with tap water?) and then discarding the container, is growing rapidly.

 

In the beginning (round about 1760) water for “therapeutic” uses was sold in glass bottles.

Then came the plastic bottle cap in 1917 and in 1941 British chemists developed a form of plastic called polyethylene terephthalate (PET).  This product was then made strong enough to contain carbonated drinks and in 1978 Coca Cola introduced the first two litre plastic bottle, which became the standard container for fizzy drinks of all sizes.

 

The French were the first to spot the potential and were first to perfect the trick of selling water at hugely marked-up prices – by marketing it as a natural miracle – initially in green glass bottles.  “Deep below the plains of southern France, in a mysterious process begun millions of years ago, nature herself adds life to the icy water of a single spring: Perrier”.

That was the advertising campaign and the Perrier brand was born.  For some time it was the only drink to be seen sipping.  By 1985 water snobbery had replaced wine snobbery and the elite ordered their water by brand name as they once did their Scotch.

 

Liquid gold rush

 

Within 5 years, the two agents of the environmental apocalypse – water and plastic bottles – were combined.  No matter that nearly a quarter of the bottled water being sold in America was actually filtered tap water; the marketing world was in overdrive, creating a liquid gold rush. Bottled water is still the fastest growing drinks market in the world.  The global market was valued at R2.3 trillion in 2013 and is expected to reach R4.2 trillion by 2020.

 

It is ironic that a product initially marketed as a health booster, through its association with plastic, became a threat to health.  More than 15 million of plastic bottles are each day incinerated, dumped in landfill sites or discarded on land or in the sea where they can enter the human food chain via contamination of marine life.  Ironic also that we drink this “life giving”  bottled water that has been shown to be contaminated with bacteria and a variety of chemicals.

The peddlers of bottled water are also shameless in their use of pristine shots of snowy mountains and glacial lakes as the sources of these waters, while ignoring the evidence of the harm that their products wreak on people and the environment.

 

90 % of teenagers have gender bending chemicals from plastic in their bodies.

 

Research has shown that young people are influenced by advertising that associates bottled water with ultimate convenience – so convenient that they ignore research data which indicates that 90 % of teenagers have gender bending chemicals from plastic in their bodies.

 

Please explain to me what is wrong with an inexpensive little water filter connected to the tap on the sink in your kitchen or kettle boiled water which you cool down and drink from a re-usable glass bottle?  Please explain to me why you would be too lazy to properly clean your glass water bottle on a daily basis.

However, I am a realist and have no doubt that there is a long way to go before people in general will kick this expensive, pointless and lethal habit of drinking water from a plastic bottle.

 

 

 

Bottled water / de / 05 11 2018

 

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Science-Backed Benefits of MSM

A bottle of MSM Powder by Lifespan

Methylsulfonylmethane, more commonly known as MSM, is a popular dietary supplement used to treat a wide array of symptoms and conditions.
It’s a sulfur-containing compound found naturally in plants, animals and humans.

MSM is widely used in the alternative medicine field and by people looking for a natural way to relieve joint pain, reduce inflammation and boost immunity.
In addition, research supports its use in treating a number of conditions from arthritis to rosacea.

MSM can Decrease Joint Pain, Which Could Improve Your Quality of Life

 

One of the most popular uses of MSM is to decrease joint or muscle pain.
It has been shown to benefit those with joint degeneration, a common cause of pain in the knees, back, hands and hips.

Joint degeneration can negatively impact your quality of life by limiting your movement and mobility.

Studies have shown that MSM significantly reduces inflammation in your body. It also inhibits the breakdown of cartilage, a flexible tissue that protects the ends of your bones in joints.
A study in 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks decreased pain, stiffness and swelling in the joints, compared to a placebo.
The group receiving the supplement also reported improved overall quality of life and less difficulty walking and getting out of bed.

Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain upon movement, plus greatly increased quality of life.

SUMMARY Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. In doing so, it can improve your quality of life.

MSM has Anti-Inflammatory Effects.

The anti-inflammatory properties of MSM are well documented by scientific research.
It’s believed that MSM inhibits NF-kB, a protein complex involved in inflammatory responses in your body.
It also reduces the production of cytokines such as tumor necrosis factor alpha (TNF-ɑ) and interleukin 6 (IL-6), which are signaling proteins linked to systemic inflammation.
Additionally, MSM can increase levels of glutathione, a potent antioxidant produced by your body.
Supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF-ɑ and IL-6, as well as increasing glutathione levels.
Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo.

SUMMARY MSM may reduce the release of molecules associated with inflammation, such as TNF-ɑ and IL-6, as well as boost levels of the powerful antioxidant glutathione.

MSM can Speed Recovery After Exercise by Reducing Muscle Damage and Stress

During exhaustive exercise, muscle damage occurs and oxidative stress increases. This causes athletes to experience muscle soreness and pain, which can hinder athletic performance and training.

MSM can naturally speed muscle recovery after intense exercise by reducing inflammation and oxidative stress.
A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.7 mile (14 km) run.

MSM may also be beneficial for reducing pain after prolonged exercise.

In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon. The MSM group reported less muscle soreness and joint pain than the placebo group.
Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise.

SUMMARY MSM may help reduce pain, muscle damage and oxidative stress after intense exercise, helping you recover more quickly.

MS helps Alleviate Arthritis Symptoms by Reducing Pain and Stiffness

Arthritis is a common inflammatory condition that causes pain, stiffness and a reduced range of motion in your joints. Since MSM has powerful anti-inflammatory properties, it’s often used as a natural alternative to drugs to improve arthritis-related symptoms.
A study in 49 people with knee osteoarthritis found that taking 3.4 grams of MSM per day for 12 weeks reduced pain and stiffness and improved physical function, compared to a placebo.
Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid.
One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone.
Another study showed that a daily supplement containing 5 grams of MSM and 7 grams of boswellic acid was more effective than glucosamine at reducing pain and improving function in people with knee osteoarthritis.
What’s more, the people who received the MSM and boswellic acid supplement were less dependent on anti-inflammatory medications than the glucosamine group.

SUMMARY MSM supplements have been shown to help reduce pain and stiffness in people with arthritis. They may also help improve physical function.

MSM may Help Relieve Allergy Symptoms by Reducing Inflammation

Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion.
Common triggers of allergic rhinitis include animal dander, pollen and moulds.

After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which lead to unpleasant symptoms.

Studies have shown that MSM may be effective in reducing symptoms of allergic rhinitis.
It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins.
A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing.
Additionally, participants experienced a significant increase in energy by day 14.

SUMMARY MSM may help reduce allergy-related symptoms — including coughing, shortness of breath, congestion, sneezing and fatigue — by reducing inflammation.

MSM can Boost Immunity and Help You Stay Healthy

Your immune system is a specialized network of tissues, cells and organs that protects your body against illness and disease.
It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity.
Sulfur compounds such as MSM play important roles in the health of your immune system.
For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity. Since it’s effective in reducing levels of inflammatory compounds like IL-6 and TNF-ɑ, MSM may reduce stress on your immune system.
Additionally, it plays a part in the creation of glutathione, your body’s master antioxidant. It may also help increase levels of this important compound.

Having adequate levels of glutathione is crucial for the overall health and function of your immune system.
A test-tube study showed that MSM effectively restored glutathione levels and reduced inflammatory markers in mouse cells that had been weakened with HIV proteins.

SUMMARY MSM may help boost your immune system by reducing inflammation and increasing glutathione levels.

MSM could Improve Skin Health by Strengthening Keratin

Keratin is a protein that acts as the main structural component in your hair, skin and nails. It contains high levels of the sulfur-containing amino acid cysteine. That’s why burnt hair gives off a characteristic sulfurous smell.

MSM may be beneficial for skin health by acting as a sulfur donor to keratin. This, in turn, can help strengthen this important protein.
MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging like wrinkles.
It may even reduce symptoms of problematic skin conditions such as rosacea, which can cause redness, irritation and inflammation of the skin.
One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin colour in people with rosacea.

SUMMARY MSM may improve skin health by strengthening keratin and reducing inflammation. It could even help reduce symptoms of certain skin conditions, as well.

MSM may Have Cancer-Fighting Properties

One of the newest areas of research involving MSM is studying its effectiveness in fighting cancer cells. Although the research is limited, the results have been promising so far.
Several test-tube studies have shown that MSM inhibits the growth of stomach, esophageal, liver, colon, skin and bladder cancer cells. It seems to do this by damaging cancer cell DNA and stimulating cancer cell death.

MSM also appears to prevent the spread of cancer cells, also known as metastasis.
A study in mice with liver cancer showed that those injected with MSM had fewer tumors, smaller tumor size and less liver damage than those who did not receive the treatment.
Another mouse study demonstrated that MSM inhibited the growth of human breast cancer cells.
Although these results are encouraging, more research is needed to determine the safety and efficacy of using MSM in cancer treatment.

SUMMARY Research has shown that MSM exhibits cancer-fighting properties in test-tube and animal studies, but more research is needed.

MSM Safety and Side Effects

MSM is considered safe and is generally well tolerated with minimal side effects.
Major regulatory agencies such as the FDA have given it the Generally Recognized As Safe (GRAS) designation. Numerous toxicity studies have been done to assess the safety of MSM and doses up to 5 grams taken 3 times per day (15 grams) appear to be safe. However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhoea. These reactions are in most cases transient. If there is a reaction, one should cut down on the daily dosage.

MSM should never be taken or mixed with alcohol since sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages.

SUMMARY MSM supplements are generally considered safe. However, they may cause side effects like nausea, diarrhoea bloating if dosage is too high.

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Getting your life back is just a little distance away.

Greetings,
As I am taking a little breather here underneath my desk, I am wondering…….

How many times in the last year have you walked into a room and forgotten why you’re there?
Drawn a blank while trying to remember the name of a long time friend?
Forgot the name of your daughter’s dog and called it Kitty…….
(Did you see the neighbour shaking his head and quickly disappearing indoors?)
Thought the car had moved from where you parked it?

Most doctors dismiss these memory lapses as a natural part of aging and say there’s nothing that can be done about it.

But what if you were told that it was possible to eliminate “senior moments” and substantially improve your memory?

And even better – if you were told it can be done completely naturally?

Or that the same herb can calm down anxiety, improve focus, enhance learning and problem solving skills?

Even more larney – that one capsule after supper might help you sleep better?

The herb that gets involved here is called Lemon balm – scientifically known as Melissa officinalis.

Lemon balm is incredibly common, grows just about everywhere and there are thousands of varieties.

But only one variety is scientifically proven to improve your memory, focus, word recall, brain power, boost your overall cognitive strength and help you sleep better.

The active ingredient is called “Bluenesse” – made from the extract of a special type of Lemon balm, only grown in Bavaria in Germany.
The exact locations of the farms where it’s grown are being guarded like a state secret.
The neuroscientists who developed “Bluenesse” formed a carefully vetted private network of farmers to grow this special Lemon balm in ideal locations.

In October last year my friend Dr Frank (M.D. and Pharmacologist) obtained some of this special Lemon balm extract and made a trial product called Memory Plus.
Being a kind man (and a friend) he afforded me some of the units. The whole lot sold out in 2 days.

Then the feedback started pouring in. The average comment can be summarised as “Wow” and “Incredible”. Only one person experienced an unwanted side effect. Drowsiness.
This can be remedied by taking the capsule at night instead of in the morning.

Here’s what two other people wrote on Doc Frank’s Website:

The day after our fist capsule, on opening the curtains and looking out, I felt great. Since then we have been more alert and talk about many things that we remember from the past.
Also short term memory”.

And

I took one capsule after a hectic day at the office. I was a nervous wreck. Within 10 minutes I found myself calm. At first I didn’t link it to Memory Plus. Then I remembered I had taken the pill. It was magic. I could relax and focus at the same time. And I slept so well afterwards”.

Published research shows that the active ingredient in Memory Plus also reduces stress.

Cortisol is the body’s stress hormone. In stressful situations, cortisol rises. This causes a “fight or flight” response. Not a lot of memory work gets done in this mode. When a lion chases you, you don’t care about the details of the trees, you only want a low hanging branch that will support you.

Under normal conditions, cortisol takes a long time to subside. If you’ve had a big fright, you will know the feeling. Hours later you are still jittery. During that time, not a lot of learning is possible.

Modern life has become a self made jungle. Each message that comes into our space has the potential to upset us. Cortisol levels stay high and we begin to forget everyday things like where we parked the car (before it moved itself) or the neighbour’s wife’s name.

Well, you don’t have to worry about these mundane little things no longer. Getting your life back is just a little distance away.

Memory Plus also contains some D-Ribose – which is a naturally occurring sugar present in all living cells. The list of many health benefits indicate that it may improve heart health, help with Fibromyalgia and Chronic Fatigue Syndrome. It is said to replenish energy levels, improves muscular strength, may help with restless leg syndrome and protects the kidneys and the brain.

The third ingredient in Memory Plus is Bioperine – which is a standardized piperine extract derived from black pepper. Piperine is what gives pepper its spicy taste and is said to have tumour inhibiting and antidepressant effects.

Memory Plus can safely be used with prescription medication. No interactions are known or expected.

DOSAGE FOR ADULTS AND CHILDREN OVER 12 YEARS:
Take 1 capsule in the morning before eating.
If there are signs of drowsiness, the capsule can be taken in the evening.
As a sleeping aid, it is best taken after supper.

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Top 5 Herbs For a Healthy Immune System

Greetings from my desk.
As winter creeps closer in, it is time to give the immune system a boost. In fact – maintaining a healthy immune system is something we should be working on all year round.
You may want to take some time and read what I’ve written about the 5 herbs that will give you a healthy immune system and how I’ve put it all together in an easy to use tincture.

Top 5 Herbs For a Healthy Immune System
Having a vibrant, healthy immune system is something that most of us take for granted, especially during our younger years when it’s usually functioning at its best. But as the body grows older, so does the immune system.
While supporting a healthy immune system is something that everyone should be doing even from a young age, it’s especially important for folks who are getting on in years. This is usually the time when things start to get a little glitchy and break down – a common part of the aging process.
If your current plan to age gracefully includes eating healthy, staying hydrated, de-stressing, and getting plenty of rest, you’re already on the right track.
But what if you could take things to a whole new level by incorporating the best of what nature has to offer into your daily regimen for added support for a strong, healthy immune system?
The following five herbs will help you do just that.

# 1. Astragalus
Astragalus (Astragalus membranaceus or Astragalus mongholicus) has deep roots in Traditional Chinese Medicine (TCM). For many thousands of years, civilizations both past and present have used this powerful adaptogenic herb to support wellness on a variety of fronts, with perhaps its most well-known benefit being in the area of immune support.
Astragalus contains more than 200 active constituents that lend to its therapeutic efficacy. Three of these – saponins, flavonoids, and polysaccharides – are particularly noteworthy as having received special attention in the scientific literature for their pronounced impact on health and wellbeing.
Saponins:
Considered to be the primary chemical constituent class found in astragalus, saponins are naturally-occurring plant phytochemicals that studies suggest can help support healthy cholesterol levels, ward off abnormal cell growth, and provide an extra boost to the immune system. According to research published in 2011, Astragalus just so happens to be the world’s richest known source of cycloartane-type saponins, which have been shown to exhibit strong cardiotonic, hypocholesteremic, antidepressive, antiblastic, and immunomodulatory properties.

Flavonoids:
These colourful antioxidant plant pigment compounds have been shown to help facilitate proper cell signaling while scavenging inflammation.
Their benefits extend beyond this to the immune system as well, as flavonoids are arch enemies to both cancer and heart disease, as demonstrated in numerous scientific studies.
Polysaccharides:
Also known as glycans, polysaccharides are molecularly-bonded simple sugars that serve as energy stores in the body. Because of this special molecular bond, polysaccharides are technically complex carbohydrates that serve as the body’s primary source of energy. Evidence suggests that polysaccharides possess powerful antimicrobial, antiviral, and anti-inflammatory properties that further lend to the bioactive nature of astragalus.

# 2. Echinacea
The Great Plains Indian tribes long used the flowers, leaves, and roots of echinacea (Echinacea purpurea) to make herbal tinctures and other botanical therapeutics to be used as an effective natural alternative to antibiotics and other drug-based medications.
Every part of the echinacea plant seems to present its own unique therapeutic flavour.
Polysaccharides:
The roots tend to contain the highest concentration of volatile oils, while the flowers and leaves contain higher amounts of polysaccharides. While polysaccharides are more closely associated with immune function, a great many of echinacea’s other constituents are also said to have an immuno-stimulating effect, including the plant’s flavonoids and essential oils.
In Germany, the above-ground portions of the echinacea plant are officially approved as a natural remedy for treating urinary and upper respiratory tract infections, as well as slow-healing wounds and colds. Echinacea is also widely used to fight against influenza, with the largest clinical trial ever conducted on the herb suggesting that it exerts a profoundly positive impact on a weakened immune system.

# 3. Frankincense
In modern times Frankincense (Boswellia carterii or Boswellia sacra) is gaining quite a reputation all around the world as a natural therapeutic with a whole lot of untapped healing potential.
Often referred to as olibanum, frankincense is commonly used as a natural remedy to calm stress and anxiety, as well as to manage pain and support an all-around healthy lifestyle free of damaging inflammation. The active ingredients of Frankincense (boswellic acid and Glucoronic acid) are believed to help facilitate the transmission of messages to the limbic system of the brain, which in turn has a direct impact on promoting optimal function within the central nervous system.
Specific to the immune system are the reported benefits of frankincense in enhancing its functionality. Studies also show that frankincense exhibits a powerful antimicrobial effect against harmful bacteria and viruses. It may even be a viable weapon against abnormal cell growth, as numerous trials have demonstrated its pro-apoptotic and anti-proliferative effects.

#4. Myrrh
Myrrh ( Commiphora myrrha) has a rich history as both an aromatic spice and a natural remedy for an assortment of ailments. Studies suggest that myrrh has a particular appetite for conditions marked by chronic inflammation. It’s also a powerful detoxifier, helping to rid the body of toxic metals such as lead.
The two constituents responsible for its therapeutic efficacy are terpenois and sesquiterpenes.
Terpenoids:
Studies show that the terpenoids in myrrh may help to prevent fats and other metabolites in plants against oxidation, and that similar benefits are possible in humans as well. Research has also shown that myrrh terpenoids possess unique anti-inflammatory properties that can help support a well-functioning body.
Sesquiterpenes:
This is another class of restorative compounds that can help support a healthy immune system in a variety of ways. The sesquiterpenes specific to myrrh possess powerful antibacterial and antifungal properties that lend to the herb’s reported effectiveness in purification and cleansing. This is why myrrh was commonly used in ancient times to embalm the dead. Sesquiterpenes are also said to be supportive in keeping inflammation at bay, as well as in helping to balance emotions and hormone levels.

#5. Turmeric
More than 6,000 peer reviewed papers confirm that turmeric (Curcuma longa) is a functional food of the highest order which can be effectively used to support health in a multitude of ways, including to help combat depression, manage pain and soothe the stomach and gut.
Curcumin:
Many people also take turmeric to help keep their cholesterol levels in check.
But where science suggests that turmeric may hold the most promise is in the area of inflammation support. Curcumin, believed-to-be the primary active constituent in turmeric, is considered by many to be one of the most potent anti-inflammatory substances known to mankind.
The combined results of many different studies reveal that curcumin can even trump many pharmaceutical drugs with its incredible ability to take on a variety of maladies, including those that affect the blood, brain, heart, gut, and central nervous system.
The anti-inflammatory properties of curcumin are further well-documented, showing that this bioactive substance interacts with many different molecular targets associated with inflammation. One research paper published in 2009 in the journal Alternative Medicine Review stated that “based on early cell culture and animal research, clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis, as well as certain types of cancer.”
The paper’s author went on to say that “Curcumin’s potent anti-inflammatory properties have led to active research on its use for a variety of inflammatory conditions, including postoperative inflammation, arthritis, uveitis, inflammatory pseudotumors, dyspepsia, irritable bowel syndrome, inflammatory bowel disease, pancreatitis, and Helicobacter pylori infection.”

LIFESPAN SENIOR BOOST
Now you might think that it would be quite a job to bring all these wonderful immune system boosting herbs together under one roof. Quite so.
And that is why we have put them all together under one cap – so to speak –
all in one bottle – as one mixture.
Professionally extracted ingredients of all five the herbs are now available in one combined tincture.

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Heart Attack and Stroke risks cut with Folic Acid

A bottle of folic acid

Most pregnant women will know the importance of taking folic acid pills. For decades a daily dose of 400 microgram (mcg) has been recommended even if a woman is simply trying to conceive – and if she then becomes pregnant, to take the folic acid for the first twelve weeks. The reason for this is that folic acid, a man made version of the B vitamin folate, protects babies in the womb against spinal and brain deformities.


A major study by University of Toronto scientists found that pills taken by millions of people – from multivitamins and vitamin D, to calcium and vitamin C – won’t reduce the risk of heart disease or help you live longer. The exception was folic acid. This seems to be the silver bullet for heart attacks and strokes.
The findings were based on a review of the results of all previous major studies. The benefits of folic acid emerged in a large study from China included in the review.
It involved more than 10 000 men and women with high blood pressure – and therefore at high risk of a stroke – and found those taking a daily 800 mcg folic acid tablet, as well as the prescribed blood pressure pills, were up to 75% less likely to have a stroke than those on blood pressure pills alone. Less than 2% of patients on folic acid supplementation and blood pressure pills for at least four years suffered a stroke.


Folic acid is a form of folate, a type of B vitamin found in green vegetables including spinach, broccoli, asparagus and Brussels sprouts as well as beans, citrus fruits and whole grains. Many breakfast cereals and some types of bread are also fortified with folate.
The body needs a regular supply of folate (about 200 mcg per day for an adult) to produce healthy red blood cells – and most people get what they need from their diet.
A daily intake of 200 mcg of folate is equivalent to six or seven asparagus spears a day, or a dozen Brussels sprouts. As we cannot store the vitamin, we need it in our diet every day.


Studies highlighting the potential benefits of folic acid for cardiovascular disease first emerged more than 20 years ago. These studies suggested that folic acid works by lowering the levels of homocysteine in the blood. Folic acid releases an enzyme that stops the formation of homocysteine. Some studies suggest eating excessive amounts of protein – such as red meat – can increase homocysteine levels, and that this damages the walls of arteries, leading to increased risk of heart disease and stroke.
A 2014 US study found taking daily folic acid supplementation could cut the risk of a heart attack by around 25%. A professor of cardiology at Barts Health NHS Trust, David Walt, says the case for folic acid is conclusive. He says a study nearly 20 years ago showed that harmful homocysteine levels can be lowered by taking folic acid. Increasing the folic acid intake could cut the number of strokes by an additional 10%.

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Urinary Tract Infection treated with D-Mannose

A bottle of D-Mannose

URINARY TRACT INFECTION TREATED WITH D-MANNOSE
UTI or cystitis is an inflammation of the urinary bladder, most often caused by an Escherichia coli bacterial infection. E coli normally live in the intestines.
UTI can also be caused by Chlamydia, a sexually transmitted organism. With this condition there is the urgent need to urinate, accompanied by a burning sensation and pain in the lower abdominal area. In extreme cases there may be blood in the urine.

THE REMEDY:
A simple sugar called D-MANNOSE has proved to be very effective in managing UTI. It is a six carbon monosaccharide or hexose and it naturally occurs in many plants and fruit, including cranberries, which are well known for their effect on bladder problems.
D-MANNOSE also occurs in some cells in the human body.
When taking D-Mannose, only small amounts get metabolized and the rest spills into the urine via the kidneys and then coating and dislodging any bacteria attached to the interior walls of the bladder and urinary tract. The offending bacteria are then literally rinsed away by normal urination. Clinical studies have demonstrated that D-Mannose promotes healthy urinary tract function by cleansing and maintaining the health of the bladder lining and urinary tract.

THE DOSAGE:
Take 4 capsules or half a teaspoon (1,5g to 2g) of powder in no more than half a glass of water three times a day for 5 days. Wait for about an hour and then drink two full glasses of water. The waiting period allows the concentrated D-Mannose more time to bind to the E.coli bacteria before flushing them with the water.
Once you have started taking D-Mannose, healthy urinary tract function should return within the first 48 hours, but keep the treatment up for the full five days.
On completion of the D-Mannose course, it is recommended that you take a 14 day to 30 day course of Ultra 4 – 8 Billion Probiotic which will help restore the healthy flora in the gut.
Make sure to watch for any flank pain or worsening symptoms that would indicate that you need to see a doctor.
Some people find it beneficial to continue with treatment for another two weeks to a month by taking one serving of D-Mannose daily.

PREVENTION:
Take D-Mannose every time you think that your urinary tract flora is compromised, with the first signs of a yeast infection, when having consumed too much sugar, through stressful times and even after intercourse.

GENERAL:
D-Mannose is believed to be safe for pregnant women, children and diabetics.
Frequent, prolonged or too high a dose of D-Mannose might cause diarrhoea, bloating and loose stools.

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