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Science-Backed Benefits of MSM

A bottle of MSM Powder by Lifespan

Methylsulfonylmethane, more commonly known as MSM, is a popular dietary supplement used to treat a wide array of symptoms and conditions.
It’s a sulfur-containing compound found naturally in plants, animals and humans.

MSM is widely used in the alternative medicine field and by people looking for a natural way to relieve joint pain, reduce inflammation and boost immunity.
In addition, research supports its use in treating a number of conditions from arthritis to rosacea.

MSM can Decrease Joint Pain, Which Could Improve Your Quality of Life


One of the most popular uses of MSM is to decrease joint or muscle pain.
It has been shown to benefit those with joint degeneration, a common cause of pain in the knees, back, hands and hips.

Joint degeneration can negatively impact your quality of life by limiting your movement and mobility.

Studies have shown that MSM significantly reduces inflammation in your body. It also inhibits the breakdown of cartilage, a flexible tissue that protects the ends of your bones in joints.
A study in 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks decreased pain, stiffness and swelling in the joints, compared to a placebo.
The group receiving the supplement also reported improved overall quality of life and less difficulty walking and getting out of bed.

Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain upon movement, plus greatly increased quality of life.

SUMMARY Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. In doing so, it can improve your quality of life.

MSM has Anti-Inflammatory Effects.

The anti-inflammatory properties of MSM are well documented by scientific research.
It’s believed that MSM inhibits NF-kB, a protein complex involved in inflammatory responses in your body.
It also reduces the production of cytokines such as tumor necrosis factor alpha (TNF-ɑ) and interleukin 6 (IL-6), which are signaling proteins linked to systemic inflammation.
Additionally, MSM can increase levels of glutathione, a potent antioxidant produced by your body.
Supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF-ɑ and IL-6, as well as increasing glutathione levels.
Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo.

SUMMARY MSM may reduce the release of molecules associated with inflammation, such as TNF-ɑ and IL-6, as well as boost levels of the powerful antioxidant glutathione.

MSM can Speed Recovery After Exercise by Reducing Muscle Damage and Stress

During exhaustive exercise, muscle damage occurs and oxidative stress increases. This causes athletes to experience muscle soreness and pain, which can hinder athletic performance and training.

MSM can naturally speed muscle recovery after intense exercise by reducing inflammation and oxidative stress.
A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.7 mile (14 km) run.

MSM may also be beneficial for reducing pain after prolonged exercise.

In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon. The MSM group reported less muscle soreness and joint pain than the placebo group.
Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise.

SUMMARY MSM may help reduce pain, muscle damage and oxidative stress after intense exercise, helping you recover more quickly.

MS helps Alleviate Arthritis Symptoms by Reducing Pain and Stiffness

Arthritis is a common inflammatory condition that causes pain, stiffness and a reduced range of motion in your joints. Since MSM has powerful anti-inflammatory properties, it’s often used as a natural alternative to drugs to improve arthritis-related symptoms.
A study in 49 people with knee osteoarthritis found that taking 3.4 grams of MSM per day for 12 weeks reduced pain and stiffness and improved physical function, compared to a placebo.
Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid.
One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone.
Another study showed that a daily supplement containing 5 grams of MSM and 7 grams of boswellic acid was more effective than glucosamine at reducing pain and improving function in people with knee osteoarthritis.
What’s more, the people who received the MSM and boswellic acid supplement were less dependent on anti-inflammatory medications than the glucosamine group.

SUMMARY MSM supplements have been shown to help reduce pain and stiffness in people with arthritis. They may also help improve physical function.

MSM may Help Relieve Allergy Symptoms by Reducing Inflammation

Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion.
Common triggers of allergic rhinitis include animal dander, pollen and moulds.

After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which lead to unpleasant symptoms.

Studies have shown that MSM may be effective in reducing symptoms of allergic rhinitis.
It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins.
A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing.
Additionally, participants experienced a significant increase in energy by day 14.

SUMMARY MSM may help reduce allergy-related symptoms — including coughing, shortness of breath, congestion, sneezing and fatigue — by reducing inflammation.

MSM can Boost Immunity and Help You Stay Healthy

Your immune system is a specialized network of tissues, cells and organs that protects your body against illness and disease.
It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity.
Sulfur compounds such as MSM play important roles in the health of your immune system.
For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity. Since it’s effective in reducing levels of inflammatory compounds like IL-6 and TNF-ɑ, MSM may reduce stress on your immune system.
Additionally, it plays a part in the creation of glutathione, your body’s master antioxidant. It may also help increase levels of this important compound.

Having adequate levels of glutathione is crucial for the overall health and function of your immune system.
A test-tube study showed that MSM effectively restored glutathione levels and reduced inflammatory markers in mouse cells that had been weakened with HIV proteins.

SUMMARY MSM may help boost your immune system by reducing inflammation and increasing glutathione levels.

MSM could Improve Skin Health by Strengthening Keratin

Keratin is a protein that acts as the main structural component in your hair, skin and nails. It contains high levels of the sulfur-containing amino acid cysteine. That’s why burnt hair gives off a characteristic sulfurous smell.

MSM may be beneficial for skin health by acting as a sulfur donor to keratin. This, in turn, can help strengthen this important protein.
MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging like wrinkles.
It may even reduce symptoms of problematic skin conditions such as rosacea, which can cause redness, irritation and inflammation of the skin.
One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin colour in people with rosacea.

SUMMARY MSM may improve skin health by strengthening keratin and reducing inflammation. It could even help reduce symptoms of certain skin conditions, as well.

MSM may Have Cancer-Fighting Properties

One of the newest areas of research involving MSM is studying its effectiveness in fighting cancer cells. Although the research is limited, the results have been promising so far.
Several test-tube studies have shown that MSM inhibits the growth of stomach, esophageal, liver, colon, skin and bladder cancer cells. It seems to do this by damaging cancer cell DNA and stimulating cancer cell death.

MSM also appears to prevent the spread of cancer cells, also known as metastasis.
A study in mice with liver cancer showed that those injected with MSM had fewer tumors, smaller tumor size and less liver damage than those who did not receive the treatment.
Another mouse study demonstrated that MSM inhibited the growth of human breast cancer cells.
Although these results are encouraging, more research is needed to determine the safety and efficacy of using MSM in cancer treatment.

SUMMARY Research has shown that MSM exhibits cancer-fighting properties in test-tube and animal studies, but more research is needed.

MSM Safety and Side Effects

MSM is considered safe and is generally well tolerated with minimal side effects.
Major regulatory agencies such as the FDA have given it the Generally Recognized As Safe (GRAS) designation. Numerous toxicity studies have been done to assess the safety of MSM and doses up to 5 grams taken 3 times per day (15 grams) appear to be safe. However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhoea. These reactions are in most cases transient. If there is a reaction, one should cut down on the daily dosage.

MSM should never be taken or mixed with alcohol since sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages.

SUMMARY MSM supplements are generally considered safe. However, they may cause side effects like nausea, diarrhoea bloating if dosage is too high.

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Top 5 Herbs For a Healthy Immune System

Greetings from my desk.
As winter creeps closer in, it is time to give the immune system a boost. In fact – maintaining a healthy immune system is something we should be working on all year round.
You may want to take some time and read what I’ve written about the 5 herbs that will give you a healthy immune system and how I’ve put it all together in an easy to use tincture.

Top 5 Herbs For a Healthy Immune System
Having a vibrant, healthy immune system is something that most of us take for granted, especially during our younger years when it’s usually functioning at its best. But as the body grows older, so does the immune system.
While supporting a healthy immune system is something that everyone should be doing even from a young age, it’s especially important for folks who are getting on in years. This is usually the time when things start to get a little glitchy and break down – a common part of the aging process.
If your current plan to age gracefully includes eating healthy, staying hydrated, de-stressing, and getting plenty of rest, you’re already on the right track.
But what if you could take things to a whole new level by incorporating the best of what nature has to offer into your daily regimen for added support for a strong, healthy immune system?
The following five herbs will help you do just that.

# 1. Astragalus
Astragalus (Astragalus membranaceus or Astragalus mongholicus) has deep roots in Traditional Chinese Medicine (TCM). For many thousands of years, civilizations both past and present have used this powerful adaptogenic herb to support wellness on a variety of fronts, with perhaps its most well-known benefit being in the area of immune support.
Astragalus contains more than 200 active constituents that lend to its therapeutic efficacy. Three of these – saponins, flavonoids, and polysaccharides – are particularly noteworthy as having received special attention in the scientific literature for their pronounced impact on health and wellbeing.
Considered to be the primary chemical constituent class found in astragalus, saponins are naturally-occurring plant phytochemicals that studies suggest can help support healthy cholesterol levels, ward off abnormal cell growth, and provide an extra boost to the immune system. According to research published in 2011, Astragalus just so happens to be the world’s richest known source of cycloartane-type saponins, which have been shown to exhibit strong cardiotonic, hypocholesteremic, antidepressive, antiblastic, and immunomodulatory properties.

These colourful antioxidant plant pigment compounds have been shown to help facilitate proper cell signaling while scavenging inflammation.
Their benefits extend beyond this to the immune system as well, as flavonoids are arch enemies to both cancer and heart disease, as demonstrated in numerous scientific studies.
Also known as glycans, polysaccharides are molecularly-bonded simple sugars that serve as energy stores in the body. Because of this special molecular bond, polysaccharides are technically complex carbohydrates that serve as the body’s primary source of energy. Evidence suggests that polysaccharides possess powerful antimicrobial, antiviral, and anti-inflammatory properties that further lend to the bioactive nature of astragalus.

# 2. Echinacea
The Great Plains Indian tribes long used the flowers, leaves, and roots of echinacea (Echinacea purpurea) to make herbal tinctures and other botanical therapeutics to be used as an effective natural alternative to antibiotics and other drug-based medications.
Every part of the echinacea plant seems to present its own unique therapeutic flavour.
The roots tend to contain the highest concentration of volatile oils, while the flowers and leaves contain higher amounts of polysaccharides. While polysaccharides are more closely associated with immune function, a great many of echinacea’s other constituents are also said to have an immuno-stimulating effect, including the plant’s flavonoids and essential oils.
In Germany, the above-ground portions of the echinacea plant are officially approved as a natural remedy for treating urinary and upper respiratory tract infections, as well as slow-healing wounds and colds. Echinacea is also widely used to fight against influenza, with the largest clinical trial ever conducted on the herb suggesting that it exerts a profoundly positive impact on a weakened immune system.

# 3. Frankincense
In modern times Frankincense (Boswellia carterii or Boswellia sacra) is gaining quite a reputation all around the world as a natural therapeutic with a whole lot of untapped healing potential.
Often referred to as olibanum, frankincense is commonly used as a natural remedy to calm stress and anxiety, as well as to manage pain and support an all-around healthy lifestyle free of damaging inflammation. The active ingredients of Frankincense (boswellic acid and Glucoronic acid) are believed to help facilitate the transmission of messages to the limbic system of the brain, which in turn has a direct impact on promoting optimal function within the central nervous system.
Specific to the immune system are the reported benefits of frankincense in enhancing its functionality. Studies also show that frankincense exhibits a powerful antimicrobial effect against harmful bacteria and viruses. It may even be a viable weapon against abnormal cell growth, as numerous trials have demonstrated its pro-apoptotic and anti-proliferative effects.

#4. Myrrh
Myrrh ( Commiphora myrrha) has a rich history as both an aromatic spice and a natural remedy for an assortment of ailments. Studies suggest that myrrh has a particular appetite for conditions marked by chronic inflammation. It’s also a powerful detoxifier, helping to rid the body of toxic metals such as lead.
The two constituents responsible for its therapeutic efficacy are terpenois and sesquiterpenes.
Studies show that the terpenoids in myrrh may help to prevent fats and other metabolites in plants against oxidation, and that similar benefits are possible in humans as well. Research has also shown that myrrh terpenoids possess unique anti-inflammatory properties that can help support a well-functioning body.
This is another class of restorative compounds that can help support a healthy immune system in a variety of ways. The sesquiterpenes specific to myrrh possess powerful antibacterial and antifungal properties that lend to the herb’s reported effectiveness in purification and cleansing. This is why myrrh was commonly used in ancient times to embalm the dead. Sesquiterpenes are also said to be supportive in keeping inflammation at bay, as well as in helping to balance emotions and hormone levels.

#5. Turmeric
More than 6,000 peer reviewed papers confirm that turmeric (Curcuma longa) is a functional food of the highest order which can be effectively used to support health in a multitude of ways, including to help combat depression, manage pain and soothe the stomach and gut.
Many people also take turmeric to help keep their cholesterol levels in check.
But where science suggests that turmeric may hold the most promise is in the area of inflammation support. Curcumin, believed-to-be the primary active constituent in turmeric, is considered by many to be one of the most potent anti-inflammatory substances known to mankind.
The combined results of many different studies reveal that curcumin can even trump many pharmaceutical drugs with its incredible ability to take on a variety of maladies, including those that affect the blood, brain, heart, gut, and central nervous system.
The anti-inflammatory properties of curcumin are further well-documented, showing that this bioactive substance interacts with many different molecular targets associated with inflammation. One research paper published in 2009 in the journal Alternative Medicine Review stated that “based on early cell culture and animal research, clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis, as well as certain types of cancer.”
The paper’s author went on to say that “Curcumin’s potent anti-inflammatory properties have led to active research on its use for a variety of inflammatory conditions, including postoperative inflammation, arthritis, uveitis, inflammatory pseudotumors, dyspepsia, irritable bowel syndrome, inflammatory bowel disease, pancreatitis, and Helicobacter pylori infection.”

Now you might think that it would be quite a job to bring all these wonderful immune system boosting herbs together under one roof. Quite so.
And that is why we have put them all together under one cap – so to speak –
all in one bottle – as one mixture.
Professionally extracted ingredients of all five the herbs are now available in one combined tincture.

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